etvax

Contract research / Process development

Our fully owned subsidiary Etvax is a CRO company with top class facilities, including a pilot plant asset, in Stockholm, Sweden. The company is focused on Research and Development, primarily of vaccines against infectious diseases. In addition to in-house development of a vaccine against Traveler’s Diarrhea, the company conducts R&D on commission from other companies. All personnel are former employees of the Swedish vaccine provider SBL Vaccin AB and with extensive experience from research on different microbial pathogens.

R&D is conducted in well-equipped laboratories with a total area of 500 sqm. Dedicated laboratory space is available for controlled fermentation of bacteria, chromatography purification of proteins, molecular biology, cell culture, and general laboratory space for analytical methods development and validation, and product characterization. Activities are conducted according to GXP’s and ICH guidelines as required.

Typically, work includes:

  • Development strategies (preclinical, clinical, and regulatory)
  • Project management
  • Genetic constructions of recombinant bacteria, expression and purification of recombinant proteins
  • Construction of Master and Working Cell Banks
  • Development of fermentation process and down-stream purification
  • Analytical methods development and validation
  • Stability testing
  • Potency assay development
  • Clinical trials
  • Interaction with Regulatory Authorities

Contact person: Nils Carlin, nils.carlin@etvax.se, +46 701 85 10 62